Antifungal Action of Methylene Blue Involves Mitochondrial Dysfunction and Disruption of Redox and Membrane Homeostasis in C. albicans

Fig. (4) Effect of MB on mitochondrial function and redox status. (a) Spot assay demonstrating depleted growth of C. albicans in presence of MB (25µg/ml) when grown with glycerol as non fermentable source in contrast with the growth in presence of glucose. (b) Reversion in the growth of C. albicans at MIC₈₀ concentration of MB when grown along with antioxidant AA at 5mM.