Virulence factor |
Initial attachment |
Bacterial aggregation |
Biofilm formation |
Biofilm degradation |
Immune modulation |
Contribution to E. faecalis IE* |
Ace |
+++ |
- |
- |
- |
- |
+++ |
Asc10 |
+ |
+++ |
++ |
- |
++ |
+++ |
Cell-wall glycolipids |
- |
- |
+ |
- |
- |
++ |
Ebp pili |
+++ |
- |
+++ |
- |
- |
+++ |
Eep |
++ |
- |
- |
- |
- |
++ |
EfbA |
++ |
- |
+ |
- |
- |
++ |
GelE |
- |
- |
- |
+++ |
+ |
++ |
Gls24 |
- |
- |
- |
- |
- |
++ |
Hemolysin |
- |
- |
- |
- |
- |
+ |
The virulence factors have been assigned a score of either +, ++, +++ or -. |
- indicates that the reviewed data does not support involvement of the virulence factor. |
+ indicates that the data suggests little involvement, ++ intermediate involvement and +++ high involvement. |
* The relative contribution of each virulence factor to the disease as compared to other involved factors. |