Article |
Studying |
Results |
P value |
Schlievert, et al., 2010 [12] |
IgGs and IgG Fabs against AS |
Immunization with IgGs against AS increased vegetation formation when exposed to Asc+ strains |
0.002 |
Immunization with IgG Fabs reduces vegetation formation when challenged with Asc+ strains |
0.05 |
Singh, et al., 2010 [3] |
rAce and anti-rAce antibodies |
Active immunization with rAce reduced the number of infected rats |
0.0001 |
Active immunization with rAce reduced the number of bacteria in the vegetations |
0.0004 |
Passive immunization with anti-rAce antibodies reduced the number of bacteria in the vegetations |
0.0231 |
Pinkston, et al., 2014 [1] |
MAb 69 |
3/10 rats given MAb 69 developed endocarditis compared to 9/10 in the control group |
0.0123 |
Singh, et al., 2015 [2] |
rEfbA |
rEfbA provided protection and reduced the total CFU bacteria recovered from vegetations |
0.008 |