Table 3: Immunization results and corresponding p-values.

Article Studying Results P value
Schlievert, et al., 2010 [12] IgGs and IgG Fabs against AS Immunization with IgGs against AS increased vegetation formation when exposed to Asc+ strains 0.002
Immunization with IgG Fabs reduces vegetation formation when challenged with Asc+ strains 0.05
Singh, et al., 2010 [3] rAce and anti-rAce antibodies Active immunization with rAce reduced the number of infected rats 0.0001
Active immunization with rAce reduced the number of bacteria in the vegetations 0.0004
Passive immunization with anti-rAce antibodies reduced the number of bacteria in the vegetations 0.0231
Pinkston, et al., 2014 [1] MAb 69 3/10 rats given MAb 69 developed endocarditis compared to 9/10 in the control group 0.0123
Singh, et al., 2015 [2] rEfbA rEfbA provided protection and reduced the total CFU bacteria recovered from vegetations 0.008