Fig. (1) Paracoccidioides brasiliensis. A – a 10% KOH preparation of sputum showing multiple budding yeast forms, with birefringent walls; B – cell-block preparation of sputum (GMS, x400) showing the mickey-mouse and pilot will; C – histopathological examination showing granulomatous lesions with fungi within multinucleated giant cells (HE, x160); D – histopathological examination showing multiple budding yeast form (GMS x160). [B,C,D courtesy of the Department of Pathology – Faculdade de Medicina de Botucatu – UNESP].