Table 3: Prevalence and intensity of the altered biochemical variables in 200 paracocidioidomycosis patients with active disease, before treatment with antifungal compounds. Comparison between the acute/subacute and the chronic form.
|
Prevalence (%) |
Intensity |
| Variables |
AF+CF |
AF |
CF |
p value |
AF |
CF |
p value |
| AST [a] |
12.7 |
21.7 |
9.6 |
0.05<p<0.10 |
2.5±1.6 |
1.5±0.6 |
0.13 |
| ALT [a] |
18.2 |
23.9 |
16.3 |
0.10 |
2.8±1.6 |
1.7±0.6 |
0.06 |
| TB [a] |
6.2 |
8.7 |
5.3 |
0.20 |
6.4±4.6 |
1.9±1.2 |
0.07 |
| CB [a] |
12.0 |
21.7 |
8.5 |
0.05 |
10.5±14.3 |
5.0±5.1 |
0.22 |
| ALP [a] |
26.0 |
50.0 |
17.8 |
<0.001 |
2.8±2.0 |
1.4±0.4 |
0.001 |
| γ-GT [a] |
32.6 |
47.8 |
24.7 |
0.02 |
5.2±6.6 |
2.7±2.9 |
0.02 |
| Triglycerides [a] |
10.7 |
4.4 |
12.7 |
0.12 |
2.20±1.70 |
1.37±0.50 |
… |
| Glucose [a] |
14.9 |
15.2 |
14.8 |
0.94 |
1.23±0.32 |
1.32±0.41 |
0.59 |
| Glucose [d] |
4.3 |
6.5 |
3.5 |
0.39 |
0.70±0.19 |
0.75±0.34 |
… |
| Cholesterol [a] |
33.7 |
18.8 |
38.7 |
0.01 |
1.26±0.37 |
1.16±0.17 |
0.18 |
| Cholesterol [d] |
66.3 |
81.3 |
61.3 |
0.01 |
0.72±0.13 |
0.81±0.13 |
≤0.001 |
| Total lipids [d] |
8.8 |
23.5 |
3.9 |
0.01 |
0.82±0.07 |
0.82±0.12 |
… |
| Calcium [a] |
8.7 |
9.3 |
8.5 |
0.87 |
1.04±0.04 |
1.04±0.04 |
… |
| Calcium [d] |
7.1 |
11.6 |
5.7 |
0.18 |
0.95±0.04 |
0.95±0.03 |
0.71 |
| Uric acid [d] |
11.9 |
3.0 |
15.4 |
0.07 |
… |
1.13±0.12 |
… |
| Phosphorus [a] |
14.3 |
14.3 |
14.3 |
1.0 |
1.06±0.02 |
1.18±0.18 |
0.18 |
| Phosphorus [d] |
4.0 |
40.0 |
37.5 |
0.79 |
0.81±0.10 |
0.86±0.10 |
0.16 |
| α1- glycoprotein [a] |
37.8 |
38.9 |
37.5 |
0.92 |
1.60±0.51 |
1.39±0.37 |
0.24 |
| Total protein [a] |
31.6 |
48.9 |
25.7 |
0.003 |
1.08±0.08 |
1.10±0.30 |
0.72 |
| Total protein [d] |
4.8 |
4.3 |
5.0 |
0.84 |
0.85±0.03 |
0.80±0.29 |
… |
| Albumin[d] |
24.2 |
30.4 |
20.2 |
0.26 |
0.74±0.21 |
0.83±0.12 |
≤0.001 |
| Globulins [a] |
73.0 |
84.4 |
69.3 |
0.046 |
1.44±0.31 |
1.23±0.20 |
≤0.001 |
| Mucoproteins [a] |
52.7 |
56.5 |
51.5 |
0.68 |
1.60±0.50 |
1.58±4.3 |
0.91 |