Use of Proviral DNA to Investigate Virus Resistance Mutations in HIV-infected Zimbabweans

Table 4: Observed HIV-1 subtype C drug resistance mutations.

Patient ID	Drug Regimen	Viral Load (copies/ml)	CD4 count (cells/ml)	Years on ART	Mutations
Patient ID	Drug Regimen	Viral Load (copies/ml)	CD4 count (cells/ml)		NRTI	NNRTI	TAMs	Total
48	1	LFU	172	4	M184V	K103N	K219Q	3
54	2	20	106	1.5	M184V T69D		D67N	3
91	1	131	127	5	M184V	Y181C		2
172	1	20	988	14	M184V		D67N K219Q K70R	4
185	1	20	351	5	T69N			1
196	1	LFU	399	5	M184V V75I	G190A V106M	L210W T215Y M41L	7

1=TDF/3TC/NVP 2= TDF/ATV/3TC, TDF, Tenofovir; 3TC, Lamivudine; NVP, Nevirapine; ATV, Atazanavir ; NRTI, nucleoside reverse transcriptase inhibitor; NNRTI, non-nucleoside reverse transcriptase inhibitor; TAMs, Thymidine analogue mutations;CD4,cluster of differentiation 4; LFU, Lost to follow-up.