Fig. (5) Anti-arthritic effect of T. rubrum in different groups. P: patient rats and Tl, T2: Treated patient rats. Septic arthritis was induced on day 0 by iv. injection of l0⁹S. aureus per rat. Tl, T2 rats received 20 and 40 mg/kg T. rubrum by IP injection on day 3. The total number and intervals of injections were 10 and 48h, respectively. Bars show the mean ± SD. (A) Time course of mean values of clinical scores of septic arthritis in groups P, Tl and T2. (B) Effect of T. rubrum on arthritis severity in different groups on day 25 (4 days after the end of T. rubrum IP injections), P versus T1 were significant (P <0.05). (C) Anti-arthritis effect of T. rubrum in different groups on day 30 (9 days after the end of T. rubrum IP injections), P versus T2 were significant (P <0.05).