| Resistance to FQs | Resistance to AGs | ||||||
|---|---|---|---|---|---|---|---|
| All patients (n = 169) |
Yes (n = 66) |
No (n = 103) |
P | Yes (n = 12) |
No (n= 157) |
P | |
| Age (years) | 66.3 ± 15.1 | 64.5 ± 15.2 | 67.5 ± 15.0 | 0.228 | 62.7 ± 17.8 | 66.6 ± 14.9 | 0.514 |
| Sex (male / female) | 115/54 (68.0) | 43/23 (65.2) | 72 /31 (69.9) | 0.612 | 9/3 (75.0) | 106/51 (67.5) | 0.754 |
| Identification at ≥30 days after hospitalization | 82 (48.5) | 35 (53.0) | 47 (45.6) | 0.430 | 7 (58.3) | 75 (47.8) | 0.557 |
| Comorbidities and conditions | |||||||
| Malignancy | 73 (43.2) | 25 (37.9) | 48 (46.6) | 0.271 | 6 (50.0) | 67 (42.7) | 0.764 |
| Diabetes | 37 (21.9) | 17 (25.8) | 20 (19.4) | 0.346 | 3 (25.0) | 34 (21.7) | 0.726 |
| Chronic dialysis | 13 (7.7) | 5 (7.6) | 8 (7.8) | 1.000 | 0 (0.0) | 13 (8.3) | 0.602 |
| Transplantation | 32 (18.9) | 16 (24.2) | 16 (15.5) | 0.166 | 2 (16.7) | 30 (19.1) | 1.000 |
| Anticancer drugs | 21 (12.4) | 10 (15.2) | 11 (10.7) | 0.475 | 3 (25.0) | 18 (11.5) | 0.174 |
| Corticosteroids (≥5 mg/day) or other immunosuppressive agents | 51 (30.2) | 25 (37.9) | 26 (25.2) | 0.088 | 2 (16.7) | 49 (31.2) | 0.514 |
| Surgery | 98 (58.0) | 34 (51.5) | 64 (62.1) | 0.202 | 6 (50.0) | 92 (58.6) | 0.562 |
| Medical devices | |||||||
| Central venous catheter | 81 (47.9) | 29 (43.9) | 52 (50.5) | 0.433 | 4 (33.3) | 77 (49.0) | 0.375 |
| Tracheal tube | 66 (39.1) | 26 (39.4) | 40 (38.8) | 1.000 | 3 (25.0) | 63 (40.1) | 0.370 |
| Ventilator | 41 (24.3) | 19 (28.8) | 22 (21.4) | 0.277 | 1 (8.3) | 40 (25.5) | 0.297 |
| Urinary catheter | 104 (61.5) | 42 (63.6) | 62 (60.2) | 0.746 | 5 (41.7) | 99 (63.1) | 0.217 |
| Feeding tube | 87 (51.5) | 33 (50.0) | 54 (52.4) | 0.875 | 6 (50.0) | 81 (51.6) | 1.000 |
| Exposure to antibiotics within 90 days | |||||||
| Antipseudomonal penicillins | 73 (43.2) | 30 (45.5) | 43 (41.7) | 0.637 | 2 (16.7) | 71 (45.2) | 0.071 |
| Other penicillins | 47 (27.8) | 20 (30.3) | 27 (26.2) | 0.600 | 4 (33.3) | 43 (27.4) | 0.740 |
| First-generation cephalosporins | 52 (30.8) | 16 (24.2) | 36 (35.0) | 0.173 | 2 (16.7) | 50 (31.8) | 0.347 |
| Second-generation cephalosporins | 18 (10.7) | 3 (4.5) | 15 (14.6) | 0.043 | 1 (8.3) | 17 (10.8) | 1.000 |
| Third-generation cephalosporins | 45 (26.6) | 20 (30.3) | 25 (24.3) | 0.476 | 2 (16.7) | 43 (27.4) | 0.519 |
| Fourth-generation cephalosporins | 14 (8.3) | 7 (10.6) | 7 (6.8) | 0.403 | 2 (16.7) | 12 (7.6) | 0.260 |
| Carbapenem | 119 (70.4) | 45 (68.2) | 74 (71.8) | 0.610 | 8 (66.7) | 111 (70.7) | 0.750 |
| Monobactam | 2 (1.2) | 2 (3.0) | 0 (0.0) | 0.151 | 0 (0.0) | 2 (1.3) | 1.000 |
| FQs | 44 (26.0) | 30 (45.5) | 14 (13.6) | <0.001 | 4 (33.3) | 40 (25.5) | 0.513 |
| AGs | 16 (9.5) | 11 (16.7) | 5 (4.9) | 0.015 | 4 (33.3) | 12 (7.6) | 0.017 |