Contraception: Influence on Vaginal Microbiota and Identification of Vaginal Lactobacilli Using MALDI-TOF MS and 16S rDNA Sequencing

Table 2: Evaluation of three months of contraception: Distribution of basic vaginal states (BVSs) according to the contraception method.

BVS¹	COCP²		CON³		RHYT⁴
BVS¹	Initial Study Distribution of BVS (n)	After 3 Months Conversion to BVS Analyzed n= 79	Initial Study Distribution of BVS (n)	After 3 Months Conversion to BVS Analyzed n= 7	Initial Study Distribution of BVS (n)	After 3 Months Conversion to BVS Analyzed n= 8
I normal microbiota	41	I = 34 II = 7	3	I = 2 II = 1	5	I = 5
II normal microbiota +VIR	13 *(2/13)	I = 2 II = 10 III = 1	2	II = 2	2	I = 1 II = 1
III intermediate microbiota	2	I = 1 III = 1	1	II = 1	-	-
IV bacterial vaginosis	16 *(1/16)	I = 3 II = 2 IV = 11	-	-	1	IV = 1
V non-specific microbial vaginitis	7 *(7/7)	I = 1 II = 3 IV = 2 V = 1	1	V = 1	-	-
TOTAL	79	Conversion to BVS I – II of microbiota normal = 10	7	Conversion to BVS II with VIR = 2	8	-

¹BVSs: Basic Vaginal States - ²COCP: Combined Oral Contraceptive Pill (levonorgestrel-ethinylestradiol) - ³CON: Condom - ⁴RHYT: Rhythm Method -*Metronidazole Treatment.