Contraception: Influence on Vaginal Microbiota and Identification of Vaginal Lactobacilli Using MALDI-TOF MS and 16S rDNA Sequencing

Table 3: Evaluation of six months of contraception: Distribution of basic vaginal states (BVSs) according to the contraception method.

BVS¹	COCP²		CON³		RHYT⁴
BVS¹	Initial Study Distribution of BVS (n)	After 6 Months Conversion to BVS Analyzed n= 75	Initial Study Distribution of BVS (n)	After 6 Months Conversion to BVS Analyzed n= 7	Initial Study Distribution of BVS (n)	After 6 Months Conversion to BVS Analyzed n= 7
I normal microbiota	41	I = 33 II = 7 IV = 1	4	I = 2 II = 2	4	I = 4
II normal microbiota +VIR	10	I = 6 II = 4	1	II = 1	2	I = 1 II = 1
III intermediate microbiota	1	I = 1	1	II = 1	-	-
IV bacterial vaginosis	14	I = 8 II = 4 IV = 2	-		1	IV = 1
V non-specific microbial vaginitis	9	I = 6 II = 2 IV = 1	1	V = 1	-	-
TOTAL	75	Conversion to BVS I – II of microbiota normal = 21	7	Conversion to BVS II with VIR= 3	7	-

¹BVSs: Basic Vaginal States - ²COCP: Combined Oral Contraceptive Pill (levonorgestrel-ethinylestradiol) - ³CON: Condom - ⁴RHYT: Rhythm Method -*Metronidazole Treatment