| Drug | Gene | Product |
|---|---|---|
| Isoniazid |
katG inhA ndh ahpC |
Catalase-peroxidase-peroxynitritase T NADH-dependent enoyl-acyl carrier protein reductase NADH dehydrogenase Alkyl hydroperoxide reductase C |
| Rifampin | rpoB | DNA-directed RNA polymerase β chain |
| Pyrazinamide | pncA | Pyrazinamidase/nicotinamidase |
| Streptomycin |
rpsL rrs gidB |
30S ribosomal protein S12 16S rRNA Glucose-inhibited division protein B |
| Amikacin-kanamycin |
rrs eis |
16S rRNA Enhanced intracellular survival protein |
| Ethionamide |
ethA inhA ethR ndh |
Monooxygenase NADH-dependent enoyl-acyl carrier protein reductase TetR family transcriptional repressor NADH dehydrogenase |
| Fluoroquinolones | gyrAB | DNA gyrase |
| para-Aminosalicylic acid |
thyA folC |
Thymidylate synthase Folylpolyglutamate synthase C |