Table 2: Gram positive and negative bacteria harboring CRISPR regions.

Organism		Ref
Gram positive	Enterococcus spp	Lyons et al., 2015 [67]
	Streptococcus thermophilus	Shariat et al., 2015 [68] Barrangou et al., 2007 [42]
	Streptococcus pneumoniae	Bikard et al., 2012 [69]
	Streptococcus pyogenes	Zheng et al., 2015 [70]
	Clostridium difficile	Hargreaves et al., 2014 [71] Andersen et al., 2016 [72]
	Lactobacillus buchneri	Briner et al., 2014 [73]
	Staphylococcus epidermidis	Marraffini et al., 2008 [74]
	Listeria monocytogenes	Di, Huiling et al., 2014 [75]
	Corynebacterium diphtheria	Mokrousov et al., [76-78]
Gram negative	Campylobacter spp	de Cárdenas, Inés et al., 2015 [79]
	Yersinia spp	Pourcel C et al., 2005 [80]
	Escherichia coli	Ishino et al., 1987 [26] Brouns et al., 2008 [43] Pul et al., 2010 [56] Diez-Villasenor et al., 2010 [81]
	Salmonella enterica	Fabre et al., 2012 [82] Li et al., 2014 [83] Le Hello et al., 2015 [84] Shariat et al., 2015 [68]
	Shigella	Guo et al., 2015 [85]
	Klebsiella pneumoniae	Ostria et al., 2015 [86]
Acid Fast Bacilli	Mycobacterium spp	Groenen et al., 1993 [28] Goyal et al., 1997 [30] Sola et al., 2015 [87]