Fig. (2) ROC curves of non-invasive biomarkers with FIB-4 index, APRI, AAR, and AARPRI for diagnosing significant liver fibrosis (F0-F1, F2-F4) in the training cohort (A), external cohort (B) and internal cohort (C). FIB-4; Fibrosis-4, APRI; AST to Platelet ratio index, AAR; AST to ALT ratio, AARPRI; AAR to Platelet ratio, AUC; area under the curve, 95% CI; 95% confidence interval.