Table 1: General features of CHB patients.

Features Training
(N=1041)		 External Cohort
(N=109)		 p values Internal Cohort
(N=104)		 p values
Male, n (%) 831 (79.8) 91 (83.5) - 81 (78.8) -
Age(Y) 35.623 36.6513 0.707996 34.7885 0.307682
ALT(U/L) 72.241 64.3578 0.663609 58.8365 0.890723
AST(U/L) 71.042 62.2201 0.4885 58.6635 0.772197
HBV (IU/L) 1.04837ᵡ107 1.250ᵡ107 0.766336 1388110 0.169515
HB(g/dl) 13.996 14.0522 0.874116 14.0173 0.980537
WBC(10^3/µl) 8.6665 8.66147 0.752923 8.48563 0.685867
PLT(10^3/µl) 252.41 249.871 0.785595 256.807 0.619191
RBC(10^6/µl) 4.8039 4.84358 0.71159 4.93374 0.349037
RDW (%) 14.219 14.1339 0.955372 14.3529 0.155264
FIB-4 1.6141 1.64646 0.123258 1.25583 0.627637
APRI .89545 .768045 0.493051 0.73476 0.682005
AAR .99662 1.01253 0.301893 0.94642 0.617333
AARPRI .75893 .809867 0.217583 0.68383 0.604218
Fibrosis, n (%)
F0 83(7.973103) 18(16.5137) - 20(19.2307) -
F1 781(75.0240) 77(70.6422) - 71(68.2692) -
F2 42(4.034582) 3(2.752294) - 5(4.807692) -
F3 62(5.955812) 5(4.587156) - 6(5.769231) -
F4 73(7.012488) 6(5.504587) - 2(1.923077) -

HBV; Hepatitis B, HB; Hemoglobin, WBC; White Blood Cells, PLT; Platelets, RBC; Red Blood Cells, RDW; Red Cells Distribution Width, FIB-4; Fibrosis-4, APRI; AST to Platelet ratio index, AAR;AST to ALT ratio, AARPRI; AAR to Platelet ratio, AST; Aspartate aminotransferase, ALT; Alanine aminotransferase, F0; No Fibrosis, F1; Portal Fibrosis without septa, F2; Portal Fibrosis with few septa, F3; Numerous septa without cirrhosis, F4; Cirrhosis.