Fig. (4) Immunogenicity and protection of recombinant LAIV-RSV/F viruses against RSV. A. RSV-specific serum IgG antibody responses measured three weeks after the second vaccine dose. The OD450 values for serum dilution 1:10 are shown. B. Protection of immunized mice against RSV A2 measured by the assessment of the RSV titers in the lungs five days after infection. Data were analyzed with one-way ANOVA, followed by Tukey's multiple comparisons tests. *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001.