Table 2: Distribution of HPV positive cases by age, gender, tobacco use, anatomical location, and grading.

Characteristics Total HPV+ HPV- X2 P value
N % N % N % - -
Age (years) - - - 0.033 0.856
18-64 44 72.1 14 31.8 30 68.2 - -
≥ 65 17 27.9 5 29.4 12 70.6 - -
Gender - - - 0.056 0.813
Male 47 77 15 31.9 32 68.1 - -
Female 14 23 4 28.6 10 71.4 - -
Tobacco - - - - - - 0.071 0.789
Yes 40 65.6 12 30 28 70 - -
No 21 34.4 7 33.3 14 66.7 - -
Anatomical location - - - 2.780 0.249
Oral cavity 27 44.3 10 37 17 63 - -
Oropharynx 12 19.7 5 41.7 7 58.3 - -
Larynx 22 36 4 18.2 18 81.8 - -
Tumor stage - - - - - - 0.108 0.742
Early (T1 and T2) 27 44.3 9 33.3 18 66.7 - -
Late (T3 and T4) 34 55.7 10 29.4 24 70.6 - -
Differentiation level - - - 0.890 0.641
Well-differentiated 14 23 3 21.4 11 78.6 - -
Moderately-differentiated 34 55.7 12 35.3 22 64.7 - -
Poorly-differentiated 13 21.3 4 30.8 9 69.2 - -

p values represent statistical comparison between HPV status and variables in each of the studied characteristics. The p values for HPV status based on differences in age (<65 vs ≥65 years old), gender (male vs female), tobacco use (smoker vs non-smoker), anatomical location (oral vs. oropharyngeal vs laryngeal), tumor stage (early vs late) or its differentiation level (well- vs, moderately- vs. poorly differentiated) were insignificant (p> 0.05)