Diagnosis of Respiratory Syncytial Virus Infection

Table 1.: Evaluation of RSV Rapid Antigen Detection Tests in Respiratory Specimens Obtained from Children and Adults with RSV Infection Confirmed by Cell Culture

Assays	% Sensitivity		% Specificity		Positive Predictive Value		Negative Predictive Value
	Children n=108	Adults n=41	Children n=127	Adults n=53	Children n=84	Adults n=34	Children n=66	Adults n=22
DFA	93	100	97	97	95	80	96	100
BD Directigen	81	25	95	98	90	50	91	94
BD Directigen EZ	72	0	98	100	93		90	82
Binax Now	94	0	100	100	100		96	94

DFA, direct immunofluorescence assay (Merifluor RSV identification reagent, Meridian Bioscience Inc., Cincinnati, Ohio); BD Directigen, direct enzyme immunoassay and BD Directigen EZ (Becton Dickinson, Cockeysville, MD); Binax Now, rapid immunoassay (Binax, Inc., Portland, Maine), modified from [⁵⁰].