Table 2.: Evaluation of RSV Rapid Antigen Detection Tests in Respiratory Specimens Obtained from Adults with RSV Infection Confirmed by Cell Culture and/or Serology and/or RT-PCR

Assays n Positive out of 60 Confirmed Infections % Sensitivity % Specificity Positive Predictive Value Negative Predictive Value
Cell culture 28 46 100 100 95
RT-PCR 49 82 100 100 98
DFA 14 23 97 44 93
VIDAS 12 20 97 40 92
BD Directigen 6 10 97 25 92

DFA, direct immunofluorescence assay (Bartels (Bartels, Inc., Issaquah, WA); VIDAS, automated enzyme immunoassay (BioMerieux, Inc., Hazelwood, MI); Directigen, direct enzyme immunoassay (Becton Dickinson, Cockeysville, MD), modified from [58].