Preparation | Survived on day 14 p.i./ total | Mean % of weight loss on day 6 p.i. | Virus isolation from tissues at day 3 pi | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Lungs | Nasal turbinates | Brain | Spleen | |||||||
No/ total | Virus titers (log10EID50/mL) | No/ total | Virus titers (log10EID50/mL) | No/ total | Virus titers (log10EID50/mL) | No/ total | Virus titers (log10EID50/mL) | |||
H7N3 LAIV 1000 MID50 | 5/5 | 1 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 |
H7N3 LAIV 100 MID50 | 5/5 | 6 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 |
PBS | 5/5 | 9 | 3/3 | 5.7 ±1.3 | 3/3 | 4.2 ±0.3 | 0/3 | ≤1.5±0.0 | 0/3 | ≤1.5±0.0 |