Table 4.: Clinical symptoms and virus isolation from respiratory organs of ferrets after inoculation of H7N3 LAIV.

Group No. Preparation Ferret No Virus dose Clinical symptoms on dpi after inoculation Organs sampling, dpi Virus isolation, PFU/0.1 g (log 10)
1 2 3 4 5 Lung Nasal turbinates
1 H7N3 LAIV 1-3 106 0 0 0 0 X 3 0 0
4-6 106 0 0 0 0 0 5 0 0
2 H7N3 LAIV 7-9 107 0 0 0 0 X 3 0 0
10-12 107 0 0 0 0 0 5 0 0
3 wt H7N3 13 107 0 0 0 0 X 3 0 1.7
14 107 0 0 0 0 X 5 1.9 1.9
15 107 0 0 0 0 X 3 0 3.7
16-18 107 0 0 0 0 0 5 0 0
4 LAIV H1N1 19-21 107 0 0 0 0 X 3 0 0
22-24 107 0 0 0 0 0 5 0 0

1 0 – absence of clinical symptoms, X- no data