Table 1: Sensitivity, specificity and accuracy for TNF-α, MMP-2 and MMP-9 in control (F0) and chronic HCV patients (F1-F4).

Cut-off F0
(No. of cases)
F1-F4
(No. of cases)
AUC p value Sensitivity Specificity PPV NPV Accuracy
TNF-α ≤0.17 15 0 1.000* <0.001 100.0 100.0 100.0 100.0 100.0
>0.17 0 25
MMP-2 ≤0.46 15 0 1.000* <0.001 100.0 100.0 100.0 100.0 100.0
>0.46 0 25
MMP-9 ≤3.05 15 0 1.000* <0.001 100.0 100.0 100.0 100.0 100.0
>3.05 0 25

AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value.
* AUC closer to 1 means higher diagnostic performance.