Table 1: Baseline Characteristics: Patient characteristics and comorbidities, aneurysmal characteristics, treatment modalities, and Cerebral Performance Category at discharge. Statistically significant if p ≤ 0.05. No/No: No beta blockade. No/Yes: Post-admission beta blockade only. Yes/Yes: Preadmission and post-admission beta blockade.

No/No
(N = 77)
No/Yes
(N = 123)
Yes/Yes
(N = 18)
p-value
Patient characteristics
Average age (± SD) 47.6 ± 16.0 54.5 ± 13.3 60.2 ± 11.6 0.0003
Gender (Female; Male) 56; 21 89; 34 15; 3 0.60
Average Glasgow Coma Score (± SD) 13.5 ± 3.2 11.8 ± 4.5 12.8 ± 3.4 0.02
Hunt and Hess (n, % group)
1 27 (35%) 18 (15%) 5 (28%) 0.02
2 29 (38%) 50 (41%) 6 (33%)
3 11 (14%) 19 (15%) 5 (28%)
4 6 (8%) 21 (17%) 1 (5%)
5 4 (5%) 15 (12%) 1 (5%)
Comorbidities (n, % group)
Average P-POSSUM (± SD) 22.1 ± 6.6 27.9 ± 8.9 29.9 ± 6.9 0.0001
Heart disease 3 (4%) 7 (6%) 6 (33%) 0.0001
Hypertension 25 (32%) 86 (70%) 14 (78%) 0.0001
Diabetes 7 (9%) 22 (18%) 2 (11%) 0.21
Dyslipidemia 6 (8%) 11 (9%) 2 (11%) 0.90
Previous stroke 6 (8%) 7 (6%) 3 (17%) 0.24
Aneurysm characteristics
Average aneurysm size (mm ±SD) 6.3 ± 6.0 6.4 ± 3.4 7.1 ± 4.2 0.81
Aneurysm location (n, % group)
Anterior 49 (64%) 77 (63%) 9 (50%) 0.43
Posterior 22 (29%) 31 (25%) 8 (44%)
Both 6 (8%) 15 (12%) 1 (6%)
Fisher Grade (n, % group)
1 5 (6%) 0 (0%) 1 (6%) 0.0002
2 10 (13%) 3 (2%) 0 (0%)
3 36 (47%) 48 (39%) 5 (28%)
4 26 (34%) 72 (59%) 12 (67%)
Treatment modalities (n, % group)
IV fluids for Triple-H therapy 53 (69%) 102 (83%) 15 (83%) 0.05
Vasopressors and/or Inotropes 19 (25%) 23 (19%) 3 (17%) 0.54
Ventricular drainage 45 (58%) 97 (79%) 13 (72%) 0.008
Angioplasty/local CCB infusion 14 (18%) 14 (11%) 3 (17%) 0.38
Clipped/Coiled (n, % group)
Clipped 52 (68%) 72 (60%) 11 (61%) 0.65
Coiled 23 (30%) 46 (38%) 6 (33%)
Both 2 (3%) 2 (2%) 1 (6%)
Cerebral performace category (n, % group)
1-2 (optimal) 61 (84%) 79 (70%) 10 (59%) 0.04
3-5 (poor) 12 (16%) 34 (30%) 7 (41%)