Table 1: Clinical and demographic data of the recruited patients at the different time points of the study.

Time x Treatment T0 x OMT
n=7
T0 x FKT
n=7
T1 x OMT
n=10
Age, yr 54.0 ± 11.6 51.0 ± 6.5 50.3 ± 7.9
Sex, M/F 5/2 5/2 8/2
Onset, Spinal/Bulbar 5/2 6/1 10/0
Duration, mo 17.1 ± 4.5
(11-25)
38.0 ± 30.5
(8-95)
35.6 ± 26.2
(13-98)
ALSFRS-R 35.0 ± 6.7
(28-46)
40.4 ± 4.0
(35-46)
33.9 ± 9.0
(16-46)
DPI 0.81 ± 0.47 *
(0.10-1.54)
0.32 ± 0.23
(0.04-0.62)
0.49 ± 0.39
(0.03-1.28)
ALSSS 29.5 ± 5.3
(24-37)
33.8 ± 2.7
(31-39)
30.6 ± 5.3
(21-38)
Norris 73.4 ± 16.9
(50-94)
90.0 ± 4.5
(85-98)
74.9 ± 19.7
(36-96)
Riluzole, Y/N 2/5 7/0 7/3

DPI, Disease Progression Index; FKT, usual care (physiotherapy); OMT, osteopathic manual treatment. Data are shown as mean ± SD. *p<0.05 vs. FKT, two-tailed Student’s t-test.

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