Fig. (4) LC-MS analyses of TXB2, PGD2 and PGE2 standards and in homogenates of lumbar cord harvested after 1 week on indicated diets (“pre-symptomatic”) or following sacrifice at terminal stage (“Terminal). The accompanying graphs present the area under the curves to facilitate comparison. All three compounds increased >2-fold for mice maintained on the 10xΩ-6 diet; TXB2 did not increase for mice maintained on the 4xΩ-3,6 diet.