Variation in symptoms of disease (1=not present anymore; 2=less present; 3= unchanged; 4= worsened): Diminished strength Paresis Difficulty in walking Difficulty in balance Sensitivity problems Sight problems Double vision Difficulty in speech Bladder disturbances Other |
1.812 1.312 1.812 1.875 2.125 1.187 1.625 1.437 1.562 0.437 |
1.558 1.302 1.559 1.360 1.360 1.377 1.408 1.750 1.711 1.209 |
0 0 0 0 0 0 0 0 0 0 |
4 4 4 4 4 4 4 4 4 4 |
Variations in type of symptoms: (1=not present anymore; 2=less present; 3= unchanged; 4= worsened): Pyramidal symptoms Sensitivity symptoms Cerebellar symptoms Brainstem symptoms Visual symptoms Sphincter disorders Other |
1.750 2.125 2.187 1.625 1.187 1.562 0.437 |
1.438 1.360 1.424 1.408 1.377 1.711 1.209 |
0 0 0 0 0 0 0 |
4 4 4 4 4 4 4 |
Knowledge of disease (0 =diminished; 1=unchanged; 2=increased) | 1.75 | 0.683 | 0 | 2 |
Source of information: Physicians Newspapers, tv, etc. Other patients Other |
0.562 0.750 0.062 0.625 |
0.512 0.447 0.250 0.250 |
0 0 0 0 |
1 1 1 1 |
Awareness of disease (0=worsened; 1=unchanged; 2=improved) | 1.5 | 0.650 | 0 | 2 |
Is the treatment beneficial? (1= yes) | 0.937 | 0.250 | 0 | 1 |
Assessment of side effects (on a scale from 0 to 5 – maximum disadvantage): Flu-like symptoms Pain in the site of injection Mental/mood changes Fatigue Insomnia Anemia Thyroiditis Other |
0.256 1.750 1.437 3.062 1.687 0.625 0.500 0.937 |
1.590 1.527 1.896 2.144 1.778 1.543 1.414 1.879 |
0 0 0 0 0 0 0 0 |
5 5 5 5 5 5 5 5 |
Assessment of treatment advantages (1=low; 5=highest benefit) | 3.812 | 1.682 | 0 | 5 |
Assessment of treatment administration (1 = no disadvantage; 5=max disadvantage) | 3.375 | 1.455 | 1 | 5 |
Interruptions of treatment (1=yes) | 0.25 | 0.447 | 0 | 1 |
How many interruptions? | 0.50 | 1.095 | 0 | 4 |
Knowledge of new therapies | 0.437 | 0.512 | 0 | 1 |
Fears about the future (1 = fears of generic worsening; 2 = fears of increased limitations) | 1.375 | 0.500 | 1 | 2 |
Risk of worsening (lower limit) | 26.666 | 19.148 | 0 | 50 |
Risk of worsening (upper limit) | 57.333 | 29.391 | 10 | 100 |