Table 2: Association between 5 –HTTLPR and risk of hazardous alcohol use.
| Scale |
Genotype |
Risk use |
OR (95% CI) |
p value |
| Low |
Moderate |
| AUDIT |
L/S – L/L |
134 (70.4%) |
67 (82.7%) |
2.01 (1.04 – 3.87) |
0.03 |
| S/S |
56 (29.5%) |
14 (17.3%) |
1.0 |
– |
| ASSIST |
S/S – L/S |
104 (86%) |
102 (68%) |
1.0 |
– |
| L/L |
17 (14.1%) |
48 (32%) |
3.06 (1.62 – 5.79) |
0.00033*
|
Note: Low and moderate risks are based on cut-off points for both scales. Cut-off point for risk use in AUDIT: 8 men, 6 women. Cut-off point for moderate-risk of consumption in the ASSIST alcohol subscale: 4.; *Significant after the Bonferroni correction.; Abbreviations: ASSIST: Alcohol, Smoking and Substance Involvement Screening Test; AUDIT: Alcohol Use Disorders Identification Test