Table 2: Association between 5 –HTTLPR and risk of hazardous alcohol use.

Scale Genotype Risk use OR (95% CI) p value
Low Moderate
AUDIT L/S – L/L 134 (70.4%) 67 (82.7%) 2.01 (1.04 – 3.87) 0.03
S/S 56 (29.5%) 14 (17.3%) 1.0
ASSIST S/S – L/S 104 (86%) 102 (68%) 1.0
L/L 17 (14.1%) 48 (32%) 3.06 (1.62 – 5.79) 0.00033*

Note: Low and moderate risks are based on cut-off points for both scales. Cut-off point for risk use in AUDIT: 8 men, 6 women. Cut-off point for moderate-risk of consumption in the ASSIST alcohol subscale: 4.; *Significant after the Bonferroni correction.; Abbreviations: ASSIST: Alcohol, Smoking and Substance Involvement Screening Test; AUDIT: Alcohol Use Disorders Identification Test

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