Table 4: Recommended Reatment Regimens for Chronic Lyme Disease

  1. Tetracycline: 1500mg/day, divided as either 500mg three times per day 20 minutes before or two hours after meals, or 750mg twice daily 20 minutes before or two hours after meals.
  2. Clarithromycin (or Erythromycin) 500mg twice daily, in combination with hydroxychloroquine 200mg twice daily with, or shortly after, meals. Azithromycin may be substituted for clarithromycin, but the dose of azithromycin of 500mg daily may not be as efficacious.