Table 5: Antibiotic Treatment of Bartonellosis

Antibiotic Dose / Day References
Azithormycin 500 mg [81, 82, 90-96]
Clarithromycin 1000 mg [89, 91-97]
Telithromycin 800 mg [89]
Rifampicin 600 mg [84, 89, 90, 91, 93, 95, 96, 98]
Trimethoprim + sulfamethoxazole 875 / 125 mg 2x daily [84, 92, 94, 98]
Ciprofloxacin 1000 mg [84, 89, 92-94, 98]
Doxycycline 400 mg [86, 89, 90, 91, 94-96]
Minocycline 200-300 mg [93]
(Other recommendations: erythromycin, roxithromycin, penicillin G, sparfloxacin, chloramphenicol, streptomycin, gentamycin, Augmentin, ticarcillin, cefotaxime, ceftriaxone, meropenem, trimethoprim and sulfamethoxazole. The information in the various publications is very contradictory. This is particularly true for gentamycin. Beta-lactam antibiotics do not act intracellularly and are therefore not suitable for the treatment of bartonellosis (author’s comment) [84,85,87,88,90,91,93,94,97,98-102]. There are substantial discrepancies between in vitro findings and in vivo efficacy.
Duration of treatment (no reliable data basis)
Acute early phase
2 weeks
Chronic course 2 - 3 months