Table 1: Coordinates and Gray Matter Values for Cortical Motor Areas in sPARKIN-MC and iPD Patients

Region Side MNI Coordinates in mm T-Value Z-Score pFDR (SVC)
x y z
Regression analysis with UPDRSIII
a) sPARKIN-MC
SMA - - - - - - -
dPMC R 22 -7 60 7.76 4.04 0.009
dPMC L -26 -12 61 6.38 3.70 0.015
b) iPD patients
SMA L -3 4 60 4.59 3.42 0.048
M1 L -63 -6 27 4.35 3.31 0.021
vPMC R 64 8 19 5.57 3.84 0.014
dPMC R 31 10 63 4.96 3.59 0.031
dPMC L -63 -5 28 4.86 3.55 0.019
Regression analysis with freezing score
a) sPARKIN-MC
SMA - - - - - - -
b) iPD patients
SMA L -2 4 66 6.92 4.31 0.002
SMA L -6 24 61 5.06 3.63 0.023
Regression analysis with disease duration
a) sPARKIN-MC
SMA - - - - - - -
b) iPD patients
SMA L -18 -8 65 3.95 3.10 0.046
M1 R 24 -28 63 4.92 3.58 0.031
dPMC L -45 -10 39 4.92 3.58 0.015

dPMC: dorsal premotor cortex, vPMC: ventral premotor cortex M1: primary motor cortex, SMA: supplementary motor area.