Fig. (4) Transient MCAO: (a) cerebral blood flow (CBF, upper row) and apparent diffusion coefficient (ADC, lower row) maps of an animal subjected to a 60-min transient occlusion. (b) Temporal evolution of lesion volumes were defined by CBF and ADC abnormalities. Final infarct volume, as determined by T2-weighted FLAIR MRI, is also shown. The grayscale bar indicates a CBF of 0 to 120 mL/100g/min and an ADC of 0 to 0.3 x 10^-3 mm²/sec.