Neural Substrates Underlying Learning-Related Changes of the Unconditioned Fear Response

Table 1: Regions that Showed Conditioned Diminution of the UCR

		Talairach Coordinates			CS+UCS vs. CS–UCS	CS–UCS vs. UCS Alone	CS+UCS vs. UCS Alone	Trait	SCR	UCS Expectancy
Region	Vol (mm³)	x	y	z	t	t	t	r	r	r
Dorsolateral PFC
Left	3739	–46.3	10.8	35.0	n.s.	–4.23	–3.81	0.04	–0.04	–0.17
Dorsomedial PFC	5670	–1.6	24.5	45.9	n.s.	–4.52	–4.18	0.04	–0.04	–0.36^*
Ventromedial PFC	515	–0.9	52.7	–0.5	n.s.	–4.33	–3.96	–0.02	0.05	–0.50^*
Anterior Insula
Left	1046	–34.6	16.3	1.7	n.s.	–3.73	–3.99	0.06	0.18	–0.48^*

Note. Location, volumes, and coordinates from Talairach and Tournoux (1988) for the center of mass for areas of activation. Significance criteria: ANOVA F[20] > 6.06, p < 0.05 (corrected); t[20] p < 0.05 (corrected). Significance criteria for two-tailed correlations:

^* indicates p < 0.05 (corrected).