Independent variables / Factor | Levels | ||
---|---|---|---|
-1 | 0 | 1 | |
X1 = PLGA amount | 25 | 75 | 125 |
X2 = PVA Concentration (%w/v) | 0.25 | 0.75 | 1.25 |
X3 = Dichloromethane volume (mL) | 2 | 4 | 6 |
Dependent variables / Response | Constraints | ||
Y1 = Particle size (nm) | Minimum | ||
Y2 = Percentage Drug entrapment (%w/w) | Maximum | ||
Y3= Poly Dispersibility Index | Minimum |