Table 1: Composition and physicochemical characteristics of ethosomes containing DAP and CLXS.

S.No. Formulation code Independent variable Zeta Potential
(mV)
Vesicle size (nm) Entrapment efficiency (%)
X1(%)* X2(%)# X3(%)$ X4(%)+ DAP CLXS
1. F1 40 5 1 5 -25.08±1.03 127±9.01 63.32 70.56
2. F2 40 7.2 0.48 4.4 -50.11±1.97 130±10.20 73.51 71.91
3. F3 40 10 1 5.2 -28.30±2.67 138±5.98 61.42 68.85
4. F4 30 7 1.3 3.5 -30.42±1.02 211±2.67 59.09 58.98
5. F5 36 7 0.55 3.5 -39.56±2.04 198±4.35 52.31 49.07
6. F6 40 5 1 5 -34.71±2.40 144±5.87 58.98 52.19
7. F7 40 10 1 3 -25.08±1.03 160±6.34 55.62 61.43
8. F8 36 11 0.6 3.5 -29.32±1.41 215±7.23 73.13 65.29
9. F9 40 7 1 5 -35.21±2.33 141±3.09 69.25 70.06

*= Percentage of alcohol, #= Percentage of propylene glycol, $= Percentage of cholesterol, += Percentage of phospholipid; All batches contain 100mg of DAP and 100mg of CLXS