Table 2: Formulation design of DAP and CLXS.

Ingredients
%w/w 		Formulation code
G1* G2** G3$ G4# G5@
Drug (DAP, CLXS) 75 75 75+75 - Optimised Ethosome
Optimized ethosome - - - - -
Carbopol 934 1 1 1 - 1
PEG 400 5 5 5 - 5
Isopropyl myristate 5 5 5 - 5
Triethenolamine 2 2 2 - 2
Water 100 100 100 - 100

* DAP plain gel; ** CLXS plain gel; $ DAP and CLXS plain gel; # Marketed DAP plain gel; @ DAP and CLXS ethosomal gel (prepared with F1 ethosomes)