Fig. (2) NPs enabling multimodal in vivo imaging of a cancer bearing body. Nanoparticles were injected into the body and guided to cancer sites in order to perform diagnosis and therapy. NP system possesses optical, photonic, radioactive, contrast, chromogenic and magnetic properties allowing live multimodal theranostic of cancer. In the homunculus, imagery shows red signal intensity where NPs were located, different techniques are used. In fluorescence imaging, molecules excited by light emit a higher intensity light detected by a CCD (Charge Coupled Device) camera, the emitted light is in the near infrared (NIR) (700-900 nm) and is characterized by high sensitivity and penetration of deep tissues. Radioactive products are used in scintigraphy and positron emission tomography, allowing functional and metabolic imaging, radioactive radiation is used to destroy cancer cells. Magnetic resonance imaging (MRI) is a method of obtaining imaging inside the body, by applying magnetic fields, MRI uses the quantum properties of atomic nuclei to locate NPs in the emitting space of the nuclear magnetic resonance (NMR) signal.