Table 3: Evidence based interventions related to integrated care 2009-2014 by setting type.

Behavioral Health into Primary Care
Author	Intervention	Design	Sample	Findings/Outcomes
Alexopoulos et al. [20]	PROSPECT: Care management intervention 15 trained care managers offered physician algorithm-based recommendations & helped with treatment compliance	RCT	(n=599) 60 years or older; had minor or major depression; suicidal ideation; seen in primary care.	Intervention group more likely to: be prescribed antidepressants or psychotherapy; have 2.2 times greater decline in suicide ideation than usual care. Intervention group patients with major depression: more attained remission than usual care & sustained through 24 month (45.4% vs 31.5%). No difference in patients with minor depression, both groups with favorable outcomes.
Echeverry et al. [21]	Antidepressant use in minority population with uncontrolled diabetes to improve HgA1c and QOL	RCT double bind placebo control	(n = 89; 75 completed) HgA1c levels of < 8% and depression	Sertraline group significantly greater decrease in HgA1c and systolic blood pressure levels (P=0.45[P<10-6]) compared with placebo. No significant difference in QOL
Hay et al. [22]	Collaborative depression care program among low-income Hispanics with diabetes. (Multifaceted Diabetes and Depression Program)	RCT	(n=387) (96.5% Hispanic) with diabetes and clinically significant depression	Intervention significantly greater health improvement compared with controls over 18-month evaluation period (4.8%; P < 0.001) and corresponding significant improvement in depression-free days (43.0; P < 0.001). Medical cost differences were not statistically significant.
Szymanski et al. [23]	Compare primary care services (PC) only with receiving primary care and mental health integration interventions (PC-MHI) or specialty mental health interventions (SMI)	Retrospective Chart Review	(n = 36, 263) Veterans in primary care setting	Patients who received same-day PC-MHI services were more likely to begin treatment, be it psychotherapy (OR: 8.16; 95 % CI: 6.54-10.17) and/or antidepressant medications (OR: 2.33, 95 % CI: 2.10 -2.58) within 12 weeks than those who received only PC services on screening days.
Primary Care into Behavioral Health
Author	Intervention	Design	Sample	Findings/Outcomes
Druss et al. [24]	Tested population-based medical care management intervention (care managers, health education and support) designed to improve primary medical care in community mental health settings.	RCT	(n = 427) Persons in a community mental health setting	Intervention group receiving significantly higher proportion of: Recommended preventive services (58.7% versus 21.8%); Evidence based services for cardiometabolic conditions (34.9% versus 27.7%); Primary care providers (71.2% versus 51.9%) Improvement on the SF-36 (8.0% versus 1.1% decline in usual care group).
McGuire et al. [25]	Clinic integrating homelessness, primary care and mental health services	Quasi exper-imental	(n = 130) Veterans homeless with serious mental illness or substance abuse	Integrated care group was more quickly enrolled in primary care and had significantly higher number of primary care visits (on average 2.3 visits more) than usual care group Individuals with more prevention services and primary care visits had fewer emergency department visits No difference in inpatient utilization or in physical health status when measured over 18 months.