Table 6: Effect(s) of single macro nutrient on RNA, proinsulin-1mRNA and hormone contents of the pancreas.

The different letters indicate significant differences between the groups at p<0.05 level.
* = Indicates significant difference between the pancreas lobes at p<0.001 level
CEBDF POLYCOSE® Casein Safflower oil CEF
RNA in GSP
(pg/mg protein)
30.1±3.3
AB
38.6±14.4
B
28.3±11.6
AD
22.02±14.8
AC
3.1±1.5
E
Proinsulin-1 mRNA in GSP (pg/mg protein) 14.0±7.3
A
32.29±17.8
B
12.7±6.1
A
7.02±5.5
C
1.1±0.54
D
Insulin in DP (ng/mg protein) 60.5±8.01*
A
99.0±31.9*
B
90.9±17.6*
B
68.5±17.0*
A
95.0±8.2*
B
Insulin in GSP (ng/mg protein) 205.7±37.4*
A
182.5±54.5*
A
187.0±52.5*
AB
173.4±49.7*
AB
153.6±35.8*
B
Glucagon in DP
(ng/mg protein)
5.70±3.38*
AB
7.48±3.53*
B
4.30±1.11*
A
4.47±1.66*
A
4.54±1.11*
A
Glucagon in GSP
(ng/mg protein)
20.17±6.69*
A
18.93±5.80*
A
12.46±6.93*
AC
24.65±10.17*
B
13.12±4.98*
AC
PP in DP
(ng/mg protein)
11.98±2.30*
A
22.80±9.93*
B
16.53±8.32*
Ab
11.96±4.89*
A
21.51±11.99*
B
PP in GSP
(ng/mg protein)
5.22±3.38*
A
3.69±2.82*
A
2.30±1.89*
B
1.82±1.43*
B
2.72±1.58*
A

PP=Pancreatic Polypeptide, DP=Duodenal Pancreas Tissue, GSP=Gastric Splanchnic Pancreas tissue, CEBDF = Cold Exposed Balanced Diet Fed, CEF = Cold Exposed Fasted.