Fig. (1) A case example of the effect of intravitreal bevacizumab. Eight months after this patient underwent plaque radiotherapy, radiation retinopathy had caused a decrease in vision to a level of 20/50. Fig. (1A) shows the retina on the day of the first bevacizumab injection, with diffuse macular hemorrhages and cotton wool spots. After one injection each month for three months, the vision in this eye had improved to 20/30. The examination at this time Fig. (1B) showed improvement in the number and size of cotton wool spots and a resolution of most of the macular hemorrhage. On the last day of follow up, 18 months after the initial injection and after 6 total bevacizumab injections, this patient's vision remained stable at 20/30. Fig. (1C) demonstrates near complete resolution of the clinical signs of radiation retinopathy.