Table 1: Renin-angiotensin system components in bulbar conjunctiva, cornea, trabecular meshwork, aqueous humor, iris, ciliary body and non-pigmented ciliary epithelium, of the human eye.

RAS component Bulbar conjunctiva Cornea Trabecular meshwork Aqueous humor Iris Ciliary body/NPE References
Prorenin x x x x x [24, 105-108]
Renin x x x x [105, 108]
AGT x x x x x [105, 109, 110]
ACE1 x x x x x x [104, 105, 110-116]
ACE2 x [104]
Ang I x x x [117, 118]
Ang II x x x x x x [111, 117-119]
Ang(1–7) x x x [93, 104]
(P)RR x x x x [105]
AT, unknown subtype x x [120, 121]
AT1R x x x x [105, 119, 122]
AT2R x x [119]
AT4R
MasR x x x [93]

Table modified and updated from the table published by Holappa et al. [123]. ACE1, -2: Angiotensin converting enzyme 1, -2; AGT: Angiotensinogen; Ang I, -II: Angiotensin I, -II; Ang(1–7): Angiotensin (1–7); AT1R, -2R, -4R: Angiotensin II type 1, 2, 4 receptor; MasR: Mas receptor; NPE: Non-pigmented ciliary epithelium; (P)RR: (pro)renin receptor; RAS: Renin-angiotensin system.