Table 4: Multivariate analysis of OSD parameters.

OSD parameters Multivariate analysis
Predictors beta 95% CI
(UCI, LCI)
p value
OSDI

Schirmer’s test

TBUT


Cornea staining
Visual acuity

Age

Age
Number of treatments

Age
Number of treatments
17.30

–0.30

–0.09
–0.66

0.10
1.22
(5.77, 28.85)

(0.53, 0.06)

(–0.18,–0.00)
(–1.06,–0.25)

(0.02, 0.18)
(0.80, 1.65)
0.004

0.014

0.048
0.002

0.016
<0.001

Backward method applied. The model fits reasonably well. Model assumptions were met. No interaction and multicollinearity problem.
Abbreviation: OSD; ocular surface disease, OSDI; ocular surface disease index, TBUT; tear break-up time.