Table 3: Sensitivity and specificity values of various analysis methods and databases compared with clinical diagnosis.

Ethnic-specific Database With Borderline Considered as Normal With Borderline Considered as Abnormal
AUC
(95% CI)
Sensitivity (%) Specificity (%) AUC
(95% CI)
Sensitivity (%) Specificity (%)
MRA
Caucasian 0.77
(0.67, 0.88)
68 87 0.83
(0.74, 0.91)
88 77
African-
American
0.79
(0.69, 0.89)
68 90 0.79
(0.70, 0.89)
80 79
Indian 0.73
(0.63, 0.84)
52 94 0.80
(0.70, 0.90)
76 85
GPS
Caucasian 0.76
(0.66, 0.87)
68 85 0.70
(0.61, 0.79)
88 52
African-
American
0.77
(0.67, 0.87)
56 98 0.77
(0.67, 0.88)
72 83
Indian 0.76
(0.66, 0.87)
68 85 0.70
(0.61, 0.79)
88 52

MRA: Moorfields Regression Analysis; GPS: Glaucoma Probability Score; AUC: Area Under Curve.