Table 2: Treatment outcomes of the different types of optic neuritis.

NMOSD MS Idiopathic p1 value p2 value p3 value
NMOSD&MS NMOSD&idiopathic MS&idiopathic
Number of patients 58 23 69
Final BCVA
- mean Log MAR
visual acuity ± SD
1.55+-1.02 0,70+-0.81 0.51+-0.74 <0.001 <0.001 0.358
- 20/20-20/60 (N, %) 18 (31.0) 12 (52.2) 47 (68.1) 0.073 <0.001 0.165
- 20/70-20/200 (N, %) 5 (8.6) 5 (21.7) 12 (17.4) 0.134 0.166 0.61
- <20/200 (N, %) 35 (60.3) 6 (26.1) 10 (14.5) 0.001 <0.001 0.262
- <10/200 (N, %) 30 (51.7) 5 (21.7) 6 (8.7) 0.003 <0.001 0.181
- no perception of light
(N, %)
6 (10.3) 0 (0) 2 (2.9) 0.062 0.063 0.59
Visual acuity outcome
- better (N, %) 30 (51.7) 18 (78.3) 49 (71.0) <0.001 <0.001 0.510
- same (N, %) 18 (31.0) 3 (13.0) 13 (18.8) 0.606 0.101 0.489
- worsen (N, %) 10 (17.2) 2 (8.7) 7 (10.1) 0.135 0.017 0.798
Recurrent attacks in affected eye (N of attack) 36 (62.1) 16 (69.6) 16 (23.2) 0.507 <0.001 <0.001
Recurrent attacks in fellow eye (N of attack) 28 (48.3) 7 (30.4) 9 (13.0) 0.094 <0.001 0.095

Abbreviations: NMOSD = Neuromyelitis Optica Spectrum Disease; MS = Multiple Sclerosis.
p1 = NMOSD versus MS; p2 = NMOSD versus idiopathic; p3 = MS versus idiopathic.
BCVA = Best Corrected Visual Acuity; LogMAR = Logarithm of the Minimal Angle of Resolution.
SD = Standard Deviation; N = Number.