Table 3: Intragroup comparison of mean values of tear osmolarity, TBUT, Schirmers 1 without and with anaesthesia at one week and 3 months post-operative.

(Mean±SD) Group A
(Cyclosporine+ Lubricant)
Group B
(Lubricant)
Group C
(Control)
- Pre 1 week 3 months Pre 1 week 3 months Pre 1 week 3 months
Tear osmolarity
(mOsm/Lt)
303.0±8.0 305.8±6.1 299.3± 10.6 299.4±10.8 309.4±13.2 302.8±13.5 303.1±12.8 310.1±10.0 310.1±14.7
p-value 0.063 0.018 0.001 0.076 0.021 0.988
TBUT (sec) 6.9 ± 2.5 6.6±2.8 8.7±3.5 6.5 ± 2.3 6.4±3.4 6.1±2.1 5.4 ± 2.9 5.0±2.6 4.4±2.6
p-value 0.87 0.03 0.113 0.508 0.36 0.05
Schirmer’s 1 without anaesthesia (mm) 17.4± 8.6 22.1±8.4 24.2±9.2 18.2± 8.9 18.2±8.5 21.7±9.3 13.4± 7.5 18.9±10.9 18.8±11.3
p-value 0.04 0.087 0.58 0.369 0.55 0.57
Schirmer’s 1 with anaesthesia
(mm)
15.6 ± 8.5 16.9±6.9 19.2±9.0 14.2 ± 7.6 12.6±6.6 15.8±8.8 16.7 ± 8.4 15.8±8.9 15.4±10.9
p-value 0.91 0.015 0.73 0.130 0.45 0.83

TBUT= Tear film break up time, SD = Standard Deviation