Table 4: Intragroup comparison of mean values of tear osmolarity, TBUT, Schirmers 1 without and with anaesthesia between pre and 3 months post-operative.

(Mean±SD) Group A
(Cyclosporine+Lubricant)
Group B
(Lubricant)
Group C
(Control)
- Pre 3 months Pre 3 months Pre 3 months
Tear osmolarity(mosm/lt) 303.0±8.0 299.3± 10.6 299.4±10.8 302.8±13.5 303.1±12.8 310.1±14.7
p-value 0.256 0.364 0.876
TBUT (sec) 6.9±2.5 8.7±3.5 6.5±2.3 6.1±2.1 5.4±2.9 4.4±2.6
p-value 0.023 0.226 0.036
Schirmer’s 1 without anaesthesia (mm) 17.4±8.6 24.2±9.2 18.2±8.9 21.7±9.3 13.4±7.5 18.8±11.3
p-value 0.004 0.909 0.431
Schirmer’s 1 with anaesthesia
(mm)
15.6±8.5 19.2±9.0 14.2±7.6 15.8±8.8 16.7±8.4 15.4±10.9
p-value 0.068 0.198 0.313
Subjective Questionnaire
(Total score=24)
11.41 ±2.2 8.35±2.15 10.08 ±1.20 10.61±2.14 11.70±1.40 14.50±2.20
p-value 0.031 0.451 0.050

TBUT= Tear film break up time, SD= standard deviation