Fig. (1) Comparison of the grade of positivity for total tear immunoglobulin E (IgE) (A), and serum dog-specific IgE (B) and IgG scores (C) among the control, seasonal, and perennial groups. The results were compared among the three groups by Kruskal-Wallis one-way analysis of variance*, while the seasonal and perennial groups were compared by the two-tailed Mann-Whitney U test**.