Different types of drusen | Sizes | Edges | Shape | Location | Risks related to AMD | References |
---|---|---|---|---|---|---|
Soft | Large (>125 ìm) | Distinct or indistinct edge | Dome-shaped | Central retina | Increases the risk of severe AMD and RPE pigmentation | [84, 85] |
Hard | Small (<63 ìm) | Distinct edge | Round | Throughout the retina | Increases risk of presentation of soft drusen | [86] |
Cuticular drusen | Small (25-75 ìm) |
Uniformly sized, “stars in the sky” pattern | Triangular, saw tooth | Around fovea | Increases the risk of CNV | [86-88] |
Reticular pseudodrusen | Large (100-250 ìm) |
Irregular borders |
Networks of oval or round lesions | Located on apical surface of RPE | Increases the risk of advanced forms of AMD | [89-92] |