Stage of AMD | Number and size of drusen | Other abnormalities | Management | |
---|---|---|---|---|
1 | Normal aging | No drusen or signs of few small (<63 µm) sized drusen in one/both eyes, or medium sized drusen in one eye | No signs of pigmentation | |
2 | Early AMD | Presence of few medium (63-125 µm) sized drusen in one or both eyes | Pigmentation | Modification of diet and lifestyle |
3 | Intermediate | Extensive medium drusen in both eyes or at least one large drusen in one eye | Geographical atrophy without macular involvement | |
4 | Advanced dry AMD | Large drusen (>125 µm) drusen or extensive medium in both eyes | Geographical atrophy extending to macula | Lifestyle management, Anti-oxidant supplements |
5 | Advanced neovascular AMD | Extensive large drusen in the fovea in both eyes besides hemorrhage and scars | CNV, fluid leakage, RPE detachment, Visual acuity less than 20/32 | Anti-VEGF therapy, laser therapy |