Table 1: Clinical Characteristics of the Eyes with Spontaneous Macular Hole Closure

Patient No. Age (Years) Gender R/L Baseline VA (Decimal) OCT Stage* Diameter of MH (µm) Days Until MH Closure† Days Until Scheduled Surgery Final VA (Decimal) Days from MH Closure to Final Visit
1 64 F L 0.8 3 150 57 89 0.8 28
2 62 M L 0.2 2 240 49 50 0.6 177
3 71 M R 0.4 4 125 70 97 0.8 441
4 72 M R 0.1 2 250 56 69 0.8 1090
4 74 M L 0.4 3 210 70 102 0.9 509
Mean ± SD 68.6 ± 5.3 195.0 ± 55.2 60.4 ± 9.3 81.4 ± 21.6

F = female; L = left eye; M = male; MH = macular hole; OCT = optical coherence tomography; R = right eye; SD = standard deviation; VA = visual acuity.
* OCT stage 2, the posterior hyaloid is still attached to the hole edge in OCT image; stage 3, the posterior hyaloid is detached from the hole edge but not from the optic disk; stage 4, complete posterior vitreous detachment.
The diameter of MH was measured as the minimal distance between the edges of the neurosensory retina detached from the retinal pigment epithelium in the horizontal or vertical OCT image that scanned through the center of MH.
† The duration from baseline to the time when the inner retina covered the hole was confirmed by OCT.
Patient No. 4 had the spontaneous closure of macular holes in both eyes; this patient was previously reported [4].