Table 5: Comparison of mfERG Values Between Different Types of IRD and Normal Values

Parameters/IRD Types USH II USH I STD RP MD CD CRD CHRD CACD BBD Normal Controls Kruskal-Wallis-Test (Chi2 Test)
RI Amplitude, nV 12.9 (7; 43.9) 12.55 (10.8; 14.3) 12.65 (7.2; 38.1) 20.3 (5.5; 39.5) 27.4 (12.5; 63) 16.9 (6.9; 33.5) 20.2 (3.7;28.1) 17.7 (4.8; 45.8) 15.4 (8.6; 30.9) nd 61.3 (25.17; 84. 82) p=0.0001*
RII Amplitude, nV 4.4 (2.3;10.1) 9.1 (6.6; 21.4) 7.8 (3.9; 25.5) 6 (2.3; 21.6) 15.4 (5.5; 39.4) 7.4 (1.9; 17.3) 5.35 (1.6;15.4) 6.4 (1.1; 21.6) 9.1 (6.6; 39.4) nd 23.25 (11.2; 36.07) p=0.0001*
RIII Amplitude, nV 6.1 (2.3;10.1) 4.5 (2.3;5.7) 8.4 (3.1; 23.7) 2.85 (0.7; 15.4) 14.8 (9.1; 25.6) 5.7 (1.2; 18.5) 2.4 (0.1; 12.8) 2.9 (0.8; 10.6) 6.45 (2.2; 9.2) nd 15.65 (8.3; 22.4) p=0.0001*
RIV Amplitude, nV 1.4 (1.1;1.5) 1.4 (0.9; 2) 8.95 (2.6; 22.8) 2.1 (0.4; 10.7) 11.7 (8.1;19.3) 2.95 (1.1; 18.3) 2.15 (0.9;11.8) 2.6 (1.2; 5.7) 6.85 (2.5;7.6) nd 11.65 (5.3;16.3) p=0.0001*
RV Amplitude, nV 1.4 (1.3;1.6) nd 10.5 (4.7; 14.03) 2.4 (0.5;10.8) 12.1 (7.4;18.8) 3.3 (1.3; 9.2) 2.1 (1.5;11.4) 2.1 (0.9; 10.15) 7.65 (3.4; 9.2) nd 10.35 (4.7; 14.03) p=0.0001*
RI Implicit time, ms 28.3 (26.6; 29.9) 27.5 (27.4; 29.2) 31.5 (24.9; 40) 30.8 (20.8; 36.7) 30 (26.7; 35.8) 31.25 (25.8; 40) 30 (25.7; 35) 33.75 (28.3; 42.3) 33.3 (33.2; 37.5) nd 29.2 (25.8; 34.16) p=0.0032*
RII Implicit time, ms 29.1 (28.3; 33.2) 29.2 (26.6; 31.6) 30.8 (28.2; 44.1) 30.7 (19.2; 37.5) 30 (15.4; 33.3) 30.7 (25;44.1) 32.9 (27.4. 41.1) 32.85 (24.2; 44) 34.55 (32.4; 39.1) nd 29.2 (26.7; 39.2) p=0.0382*
RIII Implicit time, ms 39.1 (32.5; 52.5) 29.1 (26.6; 30.8) 29.95 (28.2; 47.08) 30.8 (27.5; 41.5) 29.2 (11.4; 31.7) 32.4 (25; 40.8) 35.3 (0.8; 63.2) 32.85 (28.3; 37.4) 34.55 (32.4; 36.7) nd 28.75 (26.7; 32.41) p=0.0001*
RIV Implicit time, ms 40.8 (33.3; 48.3) 30 (26.6; 35.8) 30.4 (28.2; 46.72) 32.1 (28.3; 44) 30 (9.1; 31.7) 32.1 (28.3; 44) 37.45 (30; 60.7) 32.85 (28.3; 36.7) 34.55 (33.2; 35) nd 28.3 (25.8; 32.4) p=0.0001*
RV Implicit time, ms 40.8 (37.7; 48.3) nd 30.35 (29.1; 43.85) 32.9 (26.7; 46.6) 30 (8.5;33.2) 32.9 (26.7; 46.6) 37.45 (30.8; 69.1) 35.8 (29.9; 41.6) 32.9 (28.2; 34.2) nd 28.3 (26.7; 33;2) p=0.0001*

nd- not detectable
* -indicates that the difference was found to be statistically significant
5th and 95th quantiles are indicated in parentheses
Kruskal-Wallis test (Chi2-test for more than 2 groups) was used for the comparison of IRD subgroups and subjects with normal ophthalmological finding.

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