Study | Year | Country | N0 of patients | Mean age | Associated osteoarthritis | Conservative group | Surgical group | Main outcomes | Cross over |
---|---|---|---|---|---|---|---|---|---|
Herrlin et al. [17, 18] | 2007, 2013 | Sweden | 90 | 55 | Ahlback grades 0-1 | Standardized exercise program for 8 wk | Exercise + APM |
KOOS, Lysholm Knee Scoring Scale, Tegner Activity Scale, VAS scores | 28% |
Østerås et al. [16] | 2012 | Norway | 17 | 50 | Kellgren-Lawrence grades 0-2 | Exercise programme 3x week for 3 mo | APM | KOOS,, VAS, HAD scores, quadriceps muscle strength at 3 mo | None |
Katz et al. [19] | 2013 | United States | 351 | 58 | Kellgren-Lawrence grades 0-3 | Individualized physical therapy with progressive home exercise | Exercise + APM |
WOMAC-pf, KOOS pain scale, SF-36 physical activity scores | 30% |
Sihvonen et al. [22] | 2013 | Finland | 146 | 52 | Kellgren-Lawrence grades 0-1 | Sham surgical procedure | APM | Lysholm Knee Scoring Scale, WOMET, VAS, 15D, patient satisfaction scores | None |
Yim et al. [21] | 2013 | South Korea | 102 | 56 | Kellgren-Lawrence grades 0-1 | NSAIDs + 3 wk supervised physical exercise followed by 8 wk home exercise program | APM + strengthening exercises | Lysholm Knee Scoring Scale, VAS, patient satisfaction, Tegner Activity | 2% |
Vermesan et al. [20] | 2013 | Romania | 120 | 58 | Kellgren-Lawrence grades 0-1 | Intra-articular steroid injection | APM | Oxford knee score at 1 mo and one year | None |
Gauffin et al. [23] | 2014 | Sweden | 150 | 54 | Kellgren-Lawrence grades 0-2 | Individual exercise programme or home-based exercise programme for 3 mo | Exercise + APM |
KOOS, EQ5D, the PAS, and the symptom satisfaction scale | 21% |
Kise et al. [27] | 2016 | Norway | 140 | 50 | Kellgren-Lawrence grades 0-2. | Progressive neuromuscular and strength exercises over 12 weeks, performed 2-3 x each week (24-36 sessions) | APM | KOOS, SF-36, the one leg hop test for distance, the 6 m timed hop test, and the knee bends test | 19% |