Table 1: Summary of randomised control trials.

Study Year Country N0 of patients Mean age Associated osteoarthritis Conservative group Surgical group Main outcomes Cross over
Herrlin et al. [17, 18] 2007, 2013 Sweden 90 55 Ahlback grades 0-1 Standardized exercise program for 8 wk Exercise +
APM
KOOS, Lysholm Knee Scoring Scale, Tegner Activity Scale, VAS scores 28%
Østerås et al. [16] 2012 Norway 17 50 Kellgren-Lawrence grades 0-2 Exercise programme 3x week for 3 mo APM KOOS,, VAS, HAD scores, quadriceps muscle strength at 3 mo None
Katz et al. [19] 2013 United States 351 58 Kellgren-Lawrence grades 0-3 Individualized physical therapy with progressive home exercise Exercise +
APM
WOMAC-pf, KOOS pain scale, SF-36 physical activity scores 30%
Sihvonen et al. [22] 2013 Finland 146 52 Kellgren-Lawrence grades 0-1 Sham surgical procedure APM Lysholm Knee Scoring Scale, WOMET, VAS, 15D, patient satisfaction scores None
Yim et al. [21] 2013 South Korea 102 56 Kellgren-Lawrence grades 0-1 NSAIDs + 3 wk supervised physical exercise followed by 8 wk home exercise program APM + strengthening exercises Lysholm Knee Scoring Scale, VAS, patient satisfaction, Tegner Activity 2%
Vermesan et al. [20] 2013 Romania 120 58 Kellgren-Lawrence grades 0-1 Intra-articular steroid injection APM Oxford knee score at 1 mo and one year None
Gauffin et al. [23] 2014 Sweden 150 54 Kellgren-Lawrence grades 0-2 Individual exercise programme or home-based exercise programme for 3 mo Exercise +
APM
KOOS, EQ5D, the PAS, and the symptom satisfaction scale 21%
Kise et al. [27] 2016 Norway 140 50 Kellgren-Lawrence grades 0-2. Progressive neuromuscular and strength exercises over 12 weeks, performed 2-3 x each week (24-36 sessions) APM KOOS, SF-36, the one leg hop test for distance, the 6 m timed hop test, and the knee bends test 19%